Diagnostic Tools for Lab-on-Chip Applications Based on Coherent Imaging Microscopy
Authors: Merola F., Memmolo P., Miccio L., Bianco V., Paturzo M., Ferraro P.
Autors Affiliation: CNR, I-80078 Naples, Italy
Abstract: Today, fast and accurate diagnosis through portable and cheap devices is in high demand for the general healthcare. Lab-on-chips (LoCs) have undergone a great growth in this direction, supported by optical imaging techniques more and more refined. Here we present recent progresses in developing imaging tools based on coherent imaging microscopy that can be very useful when applied into biomicrofluidics. In some cases, the optical tweezers (OT) technique is combined with digital holography (DH), thus offering the possibility to manipulate, analyze, and measure fundamental parameters of different kinds of cells. This approach can open the route for rapid and high-throughput analysis in label-free microfluidic devices and for prognostic based on cell examination, thus allowing advancements in biomedical science.
Journal/Review: PROCEEDINGS OF THE IEEE
Volume: 103 (2) Pages from: 192 to: 204
More Information: This work was supported by Progetto Bandiera “La Fabbrica del Futuro” in the framework of the funded project “Plastic lab-on-chips for the optical manipulation of single cells” (PLUS); and by Progetto “Smart Cities”-Acquasystem: “Procedure e tecnologie innovative per una gestione pianificata ed integrata delle risorse idriche, lKeyWords: Biophotonics; diagnostics; fibroblasts; healthcare; lab-on-a-chipDOI: 10.1109/JPROC.2014.2375374Citations: 68data from “WEB OF SCIENCE” (of Thomson Reuters) are update at: 2020-10-18References taken from IsiWeb of Knowledge: (subscribers only)Connecting to view paper tab on IsiWeb: Click hereConnecting to view citations from IsiWeb: Click here