Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope
Authors: Kapsokalyvas D., Bruscino N., Alfieri D., de Giorgi V., Cannarozzo G., Cicchi R., Massi D., Pimpinelli N., Pavone FS.
Autors Affiliation: European Laboratory for Non-linear Spectroscopy (LENS), University of Florence, 50019, Sesto Fiorentino, Italy; Division of Clinical, Preventive and Oncology Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, 50129, Florence, Italy; Light4tech Firenze Srl, 50018, Scandicci, Italy; National Institute of Optics, National Research Council, 50125, Florence, Italy; Division of Human Pathology and Oncology, Department of Critical Care Medicine and Surgery, University of Florence, 50134, Florence, Italy; Department of Physics and Astronomy, University of Florence, Sesto Fiorentino, 50019, Italy
Abstract: Dermoscopy is the conventional technique used for the clinical inspection of human skin lesions. However, the identification of diagnostically relevant morphologies can become a complex task. We report on the development of a polarization multispectral dermoscope for the in vivo imaging of skin lesions. Linearly polarized illumination at three distinct spectral regions (470, 530 and 625 nm), is performed by high luminance LEDs. Processing of the acquired images, by means of spectral and polarization filtering, produces new contrast images, each one specific for melanin absorption, hemoglobin absorption, and single scattering. Analysis of such images could facilitate the identification of pathological morphologies. (C) 2013 Optical Society of America
Journal/Review: OPTICS EXPRESS
Volume: 21 (4) Pages from: 4826 to: 4840
More Information: The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreements no 228334 and no 284464 (Bioptichal) and from the Italian Ministry for Education, University and Research in the framework of the Flagship Project NANOMAX. D. Kapsokalyvas gratefully acknowledges funding from the European Commission under the Marie Curie Host Fellowships Action for Early Stage Research Training ATLAS programme (MEST-CT-2004-008048). Financial support by the Ente Cassa di Risparmio di Firenze (private foundation) is acknowledged.KeyWords: Dermatology; Light emitting diodes; Luminance; Morphology, Complex task; Conventional techniques; Dermoscopy; High luminance leds; Human skin; In-Vivo imaging; Linearly polarized; Morphological analysis; Multi-spectral; Polarization filtering; Single scattering; Skin lesion; Spectral region, Polarization, tumor marker; tumor marker, device failure analysis; devices; epiluminescence microscopy; equipment design; human; metabolism; molecular imaging; pathology; polarization microscopy; skin tumor; spectroscopy; article; epiluminescence microscopy; equipment; equipment failure; metabolism; molecular imaging; pathology; polarization microscopy; skin tumor; spectroscopy, Dermoscopy; Equipment Design; Equipment Failure Analysis; Humans; Microscopy, Polarization; Molecular Imaging; Skin Neoplasms; Spectrum Analysis; Tumor Markers, Biological, Dermoscopy; Equipment Design; Equipment Failure Analysis; Humans; Microscopy, Polarization; Molecular Imaging; Skin Neoplasms; Spectrum Analysis; Tumor Markers, BiologicaDOI: 10.1364/OE.21.004826Citations: 32data from “WEB OF SCIENCE” (of Thomson Reuters) are update at: 2019-10-20References taken from IsiWeb of Knowledge: (subscribers only)Connecting to view paper tab on IsiWeb: Click hereConnecting to view citations from IsiWeb: Click here