Scientific Results

Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope

Year: 2013

Authors: Kapsokalyvas D., Bruscino N., Alfieri D., de Giorgi V., Cannarozzo G., Cicchi R., Massi D., Pimpinelli N., Pavone FS.

Autors Affiliation: European Laboratory for Non-linear Spectroscopy (LENS), University of Florence, 50019, Sesto Fiorentino, Italy; Division of Clinical, Preventive and Oncology Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, 50129, Florence, Italy; Light4tech Firenze Srl, 50018, Scandicci, Italy; National Institute of Optics, National Research Council, 50125, Florence, Italy; Division of Human Pathology and Oncology, Department of Critical Care Medicine and Surgery, University of Florence, 50134, Florence, Italy; Department of Physics and Astronomy, University of Florence, Sesto Fiorentino, 50019, Italy

Abstract: Dermoscopy is the conventional technique used for the clinical inspection of human skin lesions. However, the identification of diagnostically relevant morphologies can become a complex task. We report on the development of a polarization multispectral dermoscope for the in vivo imaging of skin lesions. Linearly polarized illumination at three distinct spectral regions (470, 530 and 625 nm), is performed by high luminance LEDs. Processing of the acquired images, by means of spectral and polarization filtering, produces new contrast images, each one specific for melanin absorption, hemoglobin absorption, and single scattering. Analysis of such images could facilitate the identification of pathological morphologies. (C) 2013 Optical Society of America

Journal/Review: OPTICS EXPRESS

Volume: 21 (4)      Pages from: 4826  to: 4840

More Information: The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreements no 228334 and no 284464 (Bioptichal) and from the Italian Ministry for Education, University and Research in the framework of the Flagship Project NANOMAX. D. Kapsokalyvas gratefully acknowledges funding from the European Commission under the Marie Curie Host Fellowships Action for Early Stage Research Training ATLAS programme (MEST-CT-2004-008048). Financial support by the Ente Cassa di Risparmio di Firenze (private foundation) is acknowledged.
DOI: 10.1364/OE.21.004826

Citations: 32
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