Scientific Results

In-vivo optical investigation of Psoriasis

Year: 2011

Authors: Kapsokalyvas D., Cicchi R., Bruscino N., Alfieri D., Massi D., Lotti T., Pavone FS.

Autors Affiliation: European Laboratory for Non-linear Spectroscopy, University of Florence, Via Nello Carrara 1, 50019, Sesto Fiorentino, Italy;
Dept. of Dermatology, Univ. of Florence, Via della Pergola 60, 50121, Florence, Italy;
Light4tech, Via Pisana 316, 50018, Scandicci, Italy;
Dept. of Critical Care Medicine and Surgery, Viale G.B. Morgagni 85, Firenze, Italy

Abstract: Psoriasis is an autoimmune disease of the skin characterized by hyperkeratosis, hyperproliferation of the epidermis, inflammatory cell accumulation and increased dilatation of dermal papillary blood vessels. Cases of psoriasis were investigated in vivo with optical means in order to evaluate the potential of in vivo optical biopsy. A Polarization Multispectral Dermoscope was employed for the macroscopic observation. Features such as the

Conference title: Photonics West – BIOS 2011
Place: San Francisco, US

KeyWords: Autoimmune disease; Average size; Dermal papilla; Dermoscopy; Ex-vivo; High contrast; High resolution image; In-vivo; Inflammatory cells; Microscopy; Morphological features; Multi-photon microscopy; Multi-spectral; Multiphotons; Multophoton; Optical biopsies; Optical investigation; Papillary dermis; Psoriasis; skin autofluorescence; Stratum corneum, Biopsy; Blood; Blood vessels; Collagen; Polarization, Dermatology
DOI: 10.1117/12.874723

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