In-vivo morphologic and spectroscopic investigation of Psoriasis

Year: 2011

Authors: Kapsokalyvas D., Cicchi R., Bruscino N., Alfieri D., Massi D., Lotti T., Pavone FS.

Autors Affiliation: LENS, Univ. of Florence, Via Nello Carrara 1, 50019, Sesto-Fiorentino, Italy;
Dept. of Dermatology, Univ. of Florence, Via della Pergola 60, 50121, Florence, Italy;
Light4tech, Via Pisana 316, 50018, Scandicci, Italy;
Dept. of Critical Care Medicine and Surgery, Viale Morgagni 85, 50134, Florence, Italy

Abstract: Psoriasis is an autoimmune disease of the skin characterized by hyperkeratosis, hyperproliferation of the epidermis, inflammatory cell accumulation and increased dilatation of dermal papillary blood vessels. Cases of psoriasis were investigated in vivo with optical means in order to evaluate the potential of in vivo optical biopsy. A Polarization Multispectral Dermoscope was employed for the macroscopic observation. Features such as the

Conference title: European Conference on Biomedical Optics – ECBO 2011
Place: Munich, Germany

KeyWords: Autoimmune disease; Dermal papilla; Dermoscopy; Ex-vivo; High contrast; High resolution image; In-vivo; Inflammatory cells; Morphological features; Multi-spectral; Multiphoton microscopy; Multiphotons; Optical biopsies; Optical investigation; Papillary dermis; Psoriasis; Skin autofluorescence; Spectroscopic investigations; Stratum corneum, Biopsy; Blood; Blood vessels; Investments; Polarization; Spectroscopy, Dermatology
DOI: 10.1117/12.889346

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