Porous Silicon Based Resonant Mirrors for Biochemical Sensing

Year: 2008

Authors: De Tommasi E., De Stefano L., Rea I., Di Sarno V., Rotiroti L., Arcari P., Lamberti A., Sanges C., Rendina I.

Autors Affiliation: Institute for Microelectronics and Microsystems – Unit of Naples – National Council of Research, Via P. Castellino 111, 80131 Napoli, Italy;
Department of Physical Sciences, University of Naples “Federico II”, Via Cinthia, 80126 Naples, Italy;
Department of Organic Chemistry and Biochemistry, University of Naples “Federico II”, Via Cinthia, 80128 Napoli, Italy;
Department of Biochemistry and Medical Biotechnologies, University of Naples “Federico II”, Via S. Pansini 5, 80131 Napoli, Italy

Abstract: We report on our preliminary results in the realization and characterization of a porous silicon (PSi) resonant mirror (RM) for optical biosensing. We have numerically and experimentally studied the coupling between the electromagnetic field, totally reflected at the base of a high refractive index prism, and the optical modes of a PSi waveguide. This configuration is very sensitive to changes in the refractive index and/or in thickness of the sensor surface. Due to the high specific area of the PSi waveguide, very low DNA concentrations can be detected confirming that the RM could be a very sensitive and label-free optical biosensor.

Journal/Review: SENSORS

Volume: 8 (10)      Pages from: 6549  to: 6556

More Information: This work is partially supported by the FIRB Italian project RBLA033WJX_005.
KeyWords: DNA Optical Biosensors; Porous Silicon; Resonant Mirrors
DOI: 10.3390/s8106549

Citations: 33
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