The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging
Year: 2021
Authors: Lange F., Giannoni L., Tachtsidis I.
Autors Affiliation: UCL, Dept Med Phys & Biomed Engn, Biomed Opt Res Lab, London WC1E 6BT, England; CNR, Natl Inst Opt, I-50019 Sesto Fiorentino, Italy; European Lab Nonlinear Spect, I-50019 Sesto Fiorentino, Italy.
Abstract: Optical techniques based on diffuse optics have been around for decades now and are making their way into the day-to-day medical applications. Even though the physics foundations of these techniques have been known for many years, practical implementation of these technique were hindered by technological limitations, mainly from the light sources and/or detection electronics. In the past 20 years, the developments of supercontinuum laser (SCL) enabled to unlock some of these limitations, enabling the development of system and methodologies relevant for medical use, notably in terms of spectral monitoring. In this review, we focus on the use of SCL in biomedical diffuse optics, from instrumentation and methods developments to their use for medical applications. A total of 95 publications were identified, from 1993 to 2021. We discuss the advantages of the SCL to cover a large spectral bandwidth with a high spectral power and fast switching against the disadvantages of cost, bulkiness, and long warm up times. Finally, we summarize the utility of using such light sources in the development and application of diffuse optics in biomedical sciences and clinical applications.
Journal/Review: APPLIED SCIENCES-BASEL
Volume: 11 (10) Pages from: 4616-1 to: 4616-32
More Information: This research was funded by the Medical Research Council (MR/S003134/1).KeyWords: supercontinuum laser; NIRS; tissue optics; diffuse opticsDOI: 10.3390/app11104616Citations: 5data from “WEB OF SCIENCE” (of Thomson Reuters) are update at: 2025-01-12References taken from IsiWeb of Knowledge: (subscribers only)