Transition between Random and Periodic Electron Currents on a DNA Chain

Year: 2021

Authors: Faraji E., Franzosi R., Mancini S., Pettini M.

Autors Affiliation: Aix Marseille Univ, Univ Toulon, CNRS, CPT, F-13288 Marseille, France; CNRS, Ctr Phys Theor, UMR7332, F-13288 Marseille, France; Univ Camerino, Sch Sci & Technol, I-62032 Camerino, Italy; Ist Nazl Fis Nucl, Sez Perugia, I-06123 Perugia, Italy; QSTAR, Largo Enrico Fermi 2, I-50125 Florence, Italy; INO CNR, Largo Enrico Fermi 2, I-50125 Florence, Italy.

Abstract: By resorting to a model inspired to the standard Davydov and Holstein-Fröhlich models, in the present paper we study the motion of an electron along a chain of heavy particles modeling a sequence of nucleotides proper to a DNA fragment. Starting with a model Hamiltonian written in second quantization, we use the Time Dependent Variational Principle to work out the dynamical equations of the system. It can be found that, under the action of an external source of energy transferred to the electron, and according to the excitation site, the electron current can display either a broad frequency spectrum or a sharply peaked frequency spectrum. This sequence-dependent charge transfer phenomenology is suggestive of a potentially rich variety of electrodynamic interactions of DNA molecules under the action of electron excitation. This could imply the activation of interactions between DNA and transcription factors, or between DNA and external electromagnetic fields.

Journal/Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Volume: 22, 7361      Pages from: 1  to: 16

KeyWords: DNA chains; Davydov model; electron current; Holstein-Fröhlich model; time dependent variational principle
DOI: 10.3390/ijms22147361

Citations: 1
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