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Author: Costantini Irene Category: Papers Journals 

1) Optical Clearing and Labeling for Light-sheet Fluorescence Microscopy in Large-scale Human Brain Imaging in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
By: Di Meo D., Ramazzotti J., Scardigli M., Cheli F., Pesce L., Brady N., Mazzamuto G., Costantini I., Pavone FS. Year: 2024 (Cit.: 0 DOI: 10.3791/65960)

2) Deep learning-based localization algorithms on fluorescence human brain 3D reconstruction: a comparative study using stereology as a reference in SCIENTIFIC REPORTS
By: Checcucci C., Wicinski B., Mazzamuto G., Scardigli M., Ramazzotti J., Brady N., Pavone FS., Hof PR., Costantini I., Frasconi P. Year: 2024 (Cit.: 0 DOI: 10.1038/s41598-024-65092-3)

3) Segmentation of supragranular and infragranular layers in ultra-high-resolution 7T ex vivo MRI of the human cerebral cortex in CEREBRAL CORTEX
By: Zeng XR., Puonti O., Sayeed A., Herisse R., Mora J., Evancic K., Varadarajan D., Balbastre Y., Costantini I., Scardigli M., Ramazzotti J., Di Meo D., Mazzamuto G., Pesce L., Brady N., Cheli F., Pavone F.S., Hof P.R., Frost R., Augustinack J., Van der Kouwe A., Iglesias J.E., Fischl B. Year: 2024 (Cit.: 0 DOI: 10.1093/cercor/bhae362)

4) Fiber enhancement and 3D orientation analysis in label-free two-photon fluorescence microscopy in SCIENTIFIC REPORTS
By: Sorelli Michele; Costantini Irene; Bocchi Leonardo; Axer Markus; Pavone Francesco Saverio; Mazzamuto Giacomo Year: 2023 (Cit.: 3 DOI: 10.1038/s41598-023-30953-w)

5) A Guide to Perform 3D Histology of Biological Tissues with Fluorescence Microscopy in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
By: Laurino A., Franceschini A., Pesce L., Cinci L., Montalbano A., Mazzamuto G., Sancataldo G., Nesi G., Costantini I., Silvestri L., Pavone FS. Year: 2023 (Cit.: 5 DOI: 10.3390/ijms24076747)

6) Brain-wide neuron quantification toolkit reveals strong sexual dimorphism in the evolution of fear memory in CELL REPORTS
By: Franceschini A., Mazzamuto G., Checcucci C., Chicchi L., Fanelli D., Costantini I., Passani MB., Silva BA., Pavone FS., Silvestri L. Year: 2023 (Cit.: 2 DOI: 10.1016/j.celrep.2023.112908)

7) A cellular resolution atlas of Broca’s area in SCIENCE ADVANCES
By: Costantini I., Morgan L., Yang JR., Balbastre Y., Varadarajan D., Pesce L., Scardigli M., Mazzamuto G., Gavryusev V., Castelli FM., Roffilli M., Silvestri L., Laffey J., Raia S., Varghese M., Wicinski B., Chang SB., Chen IA., Wang H., Cordero D., Vera M., Nolan J., Nestor K., Mora J., Iglesias JE., Pallares EG., Evancic K., Augustinack JC., Fogarty M., Dalca AV., Frosch MP., Magnain C., Frost R., van der Kouwe A., Chen SC., Boas DA., Pavone FS., Fischl B., Hof PR. Year: 2023 (Cit.: 8 DOI: 10.1126/sciadv.adg3844)

8) 3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy in COMMUNICATIONS BIOLOGY
By: Pesce Luca; Scardigli Marina; Gavryusev Vladislav; Laurino Annunziatina; Mazzamuto Giacomo; Brady Niamh; Sancataldo Giuseppe; Silvestri Ludovico; Destrieux Christophe; Hof Patrick R.; Costantini Irene; Pavone Francesco S. Year: 2022 (Cit.: 22 DOI: 10.1038/s42003-022-03390-0)

9) Neurophotonic tools for microscopic measurements and manipulation: status report in NEUROPHOTONICS
By: Abdelfattah AS., Ahuja S., Akkin T., Allu SR., Brake J., Boas DA., Buckley EM., Campbell RE., Chen AI., Cheng XJ., Cizmbr T., Costantini I., De Vittorio M., Devor A., Doran PR., El Khatib M., Emiliani V., Fomin-Thunemann N., Fainman Y., Fernandez-Alfonso T., Ferri CGL., Gilad A., Han X., Harris A., Hillman EMC., Hochgeschwender U., Holt MG., Ji N., Kiliz K., Lake EMR., Li L., Li TQ., Mdchler P., Miller EW., Mesquita RC., Nadella KMNS., Ndgerl UV., Nasu Y., Nimmerjahn A., Ondrbckovb P., Pavone FS., Campos CP., Peterka DS., Pisano F., Pisanello F., Puppo F., Sabatini BL., Sadegh S., Sakadzic S., Shoham S., Shroff SN., Silver RA., Sims RR., Smith SL., Srinivasan VJ., Thunemann M., Tian L., Tian L., Troxler T., Valera A., Vaziri A., Vinogradov SA., Vitale F., Wang LV., Uhlnrovb H., Xu C., Yang CHE., Yang MH., Yellen G., Yizhar O., Zhao YX. Year: 2022 (Cit.: 29 DOI: 10.1117/1.NPh.9.S1.013001)

10) Automated computation of nerve fibre inclinations from 3D polarised light imaging measurements of brain tissue in SCIENTIFIC REPORTS
By: Menzel M., Reuter JA., Graessel D., Costantini I., Amunts K., Axer M. Year: 2022 (Cit.: 4 DOI: 10.1038/s41598-022-08140-0)

11) Autofluorescence enhancement for label‑free imaging of myelinated fibers in mammalian brains in SCIENTIFIC REPORTS
By: Costantini I., Baria E., Sorelli M., Matuschke F., Giardini F., Menzel M., Mazzamuto G., Silvestri L., Cicchi R., Amunts K., Axer M., Pavone F.S. Year: 2021 (Cit.: 19 DOI: 10.1038/s41598-021-86092-7)

12) Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques in FRONTIERS IN NEUROANATOMY
By: Scardigli M., Pesce L., Brady N., Mazzamuto G., Gavryusev V., Silvestri L., Hof PR., Destrieux C., Costantini I., Pavone FS. Year: 2021 (Cit.: 10 DOI: 10.3389/fnana.2021.752234)

13) Large-scale, cell-resolution volumetric mapping allows layer-specific investigation of human brain cytoarchitecture in BIOMEDICAL OPTICS EXPRESS
By: Costantini I., Mazzamuto G., Roffilli M., Laurino A., Castelli FM., Neri M., Lughi G., Simonetto A., Lazzeri E., Pesce L., Destrieux C., Silvestri L., Conti V., Guerrini R., Pavone FS Year: 2021 (Cit.: 17 DOI: 10.1364/BOE.415555)

14) Universal autofocus for quantitative volumetric microscopy of whole mouse brains in NATURE METHODS
By: Silvestri L., Mullenbroich MC., Costantini I., Di Giovanna AP., Mazzamuto G., Franceschini A., Kutra D., Kreshuk A., Checcucci C., Toresano LO., Frasconi P., Sacconi L., Pavone FS. Year: 2021 (Cit.: 31 DOI: 10.1038/s41592-021-01208-1)

15) Exploring the human cerebral cortex using confocal microscopy in PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
By: Pesce Luca; Laurino Annunziatina; Scardigli Marina; Yang Jiarui; Boas David A.; Hof Patrick R.; Destrieux Christophe; Costantini Irene; Pavone Francesco Saverio Year: 2021 (Cit.: 12 DOI: 10.1016/j.pbiomolbio.2021.09.001)

16) Mesoscopic Optical Imaging of Whole Mouse Heart in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
By: Giardini F., Lazzeri E., Olianti C., Beconi G., Costantini I., Silvestri L., Cerbai E., Pavone FS., Sacconi L. Year: 2021 (Cit.: 4 DOI: 10.3791/62795)

17) Quantification of Myocyte Disarray in Human Cardiac Tissue in FRONTIERS IN PHYSIOLOGY
By: Giardini F., Lazzeri E., Vitale G., Ferrantini C., Costantini I., Pavone FS., Poggesi C., Bocchi L., Sacconi L. Year: 2021 (Cit.: 5 DOI: 10.3389/fphys.2021.750364)

18) Towards a clearer view of sympathetic innervation of cardiac and skeletal muscles in PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
By: Di Bona A., Vita V., Costantini I., Zaglia T. Year: 2020 (Cit.: 18 DOI: 10.1016/j.pbiomolbio.2019.07.003)

19) Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early Genes in FRONTIERS IN NEUROSCIENCE
By: Franceschini A., Costantini I., Pavone FS., Silvestri L. Year: 2020 (Cit.: 27 DOI: 10.3389/fnins.2020.569517)

20) 3D imaging and morphometry of the heart capillary system in spontaneously hypertensive rats and normotensive controls in SCIENTIFIC REPORTS
By: Olianti C., Costantini I., Giardini F., Lazzeri E., Crocini C., Ferrantini C., Pavone FS., Camici PG., Sacconi L. Year: 2020 (Cit.: 17 DOI: 10.1038/s41598-020-71174-9)

21) Toward a High-Resolution Reconstruction of 3D Nerve Fiber Architectures and Crossings in the Brain Using Light Scattering Measurements and Finite-Difference Time-Domain Simulations in PHYSICAL REVIEW X
By: Menzel M., Axer M., De Raedt H., Costantini I., Silvestri L., Pavone FS., Amunts K., Michielsen K. Year: 2020 (Cit.: 17 DOI: 10.1103/PhysRevX.10.021002)

22) Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters in NEUROPHOTONICS
By: Yang JR., Chen IA., Chang SB., Tang JB., Lee B., Kiliz K., Sunil S., Wang H., Varadarajan D., Magnain C., Chen SC., Costantini I., Pavone F., Fischl B., Boas DA. Year: 2020 (Cit.: 11 DOI: 10.1117/1.NPh.7.4.045005)

23) In-vivo and ex-vivo optical clearing methods for biological tissues: review in BIOMEDICAL OPTICS EXPRESS
By: Costantini I., Cicchi R., Silvestri L., Vanzi F., Pavone F.S. Year: 2019 (Cit.: 114 DOI: 10.1364/BOE.10.005251)

24) Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery in JOURNAL OF PHYSIOLOGY-LONDON
By: Pianca N., Di Bona A., Lazzeri E., Costantini I., Franzoso M., Prando V., Armani A., Rizzo S., Fedrigo M., Angelini A., Basso C., Pavone FS., Rubart M., Sacconi L., Zaglia T., Mongillo M. Year: 2019 (Cit.: 37 DOI: 10.1113/JP276200)

25) Publisher Correction: Whole-Brain Vasculature Reconstruction at the Single Capillary Level (Scientific Reports, (2018), 8, 1, (12573), 10.1038/s41598-018-30533-3) in SCIENTIFIC REPORTS
By: Di Giovanna A.P., Tibo A., Silvestri L., Mullenbroich M.C., Costantini I., Allegra Mascaro A.L., Sacconi L., Frasconi P., Pavone F.S. Year: 2019 (Cit.: 0 DOI: 10.1038/s41598-019-42216-8)

26) Whole-Brain Vasculature Reconstruction at the Single Capillary Level in SCIENTIFIC REPORTS
By: Di Giovanna A.P., Tibo A., Silvestri L., Muellenbroich M.C., Costantini I., Allegra Mascaro A.L., Sacconi L., Frasconi P., Pavone F.S. Year: 2018 (Cit.: 85 DOI: 10.1038/s41598-018-30533-3)

27) High-fidelity imaging in brain-wide structural studies using light-sheet microscopy in ENEURO
By: Müllenbroich M.C., Silvestri L., Di Giovanna A.P., Mazzamuto G., Costantini I., Sacconi L., Pavone F.S. Year: 2018 (Cit.: 13 DOI: 10.1523/ENEURO.0124-18.2018)

28) Clearing of fixed tissue: a review from a microscopist´s perspective in JOURNAL OF BIOMEDICAL OPTICS
By: Silvestri L., Costantini I., Sacconi L., Pavone F.S. Year: 2016 (Cit.: 104 DOI: 10.1117/1.JBO.21.8.081205)

29) Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging in BIOMEDICAL OPTICS EXPRESS
By: Allegra Mascaro A.L., Costantini I., Margoni E., Iannello G., Bria A., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 13 DOI: 10.1364/BOE.6.004483)

30) A versatile clearing agent for multi-modal brain imaging in SCIENTIFIC REPORTS
By: Costantini I., Ghobril J.P., Di Giovanna A.P., Allegra Mascaro A. L., Silvestri L., Müllenbroich M.C., Onofri L., Conti V., Vanzi F., Sacconi L., Guerrini R., Markram H., Iannello G., Pavone F.S. Year: 2015 (Cit.: 190 DOI: 10.1038/srep09808)

31) Comprehensive optical and data management infrastructure for high-throughput light-sheet microscopy of whole mouse brains in NEUROPHOTONICS
By: Muellenbroich M.C., Silvestri L., Onofri L., Costantini I., Van’t Hoff M., Sacconi L., Iannello G., Pavone F.S. Year: 2015 (Cit.: 17 DOI: 10.1117/1.NPh.2.4.041404)

32) Correlative two-photon and light sheet microscopy in METHODS
By: Silvestri L., Allegra Mascaro A. M., Costantini I., Sacconi L., Pavone F. S. Year: 2014 (Cit.: 26 DOI: 10.1016/j.ymeth.2013.06.013)

33) Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis in FRONTIERS IN MICROBIOLOGY
By: Rosentul D.C., Delsing C.E., Jaeger M., Plantinga T.S., Oosting M., Costantini I., Venselaar H., Joosten L.A.B., van der Meer J.W.M., Dupont B., Kullberg B.-J., Sobel J.D., Netea M.G. Year: 2014 (Cit.: 48 DOI: 10.3389/fmicb.2014.00483)

34) Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
By: Silvestri L., Bria A., Costantini I., Sacconi L., Peng H., Iannello G., Pavone F.S. Year: 2013 (Cit.: 17 DOI: 10.3791/50696)

35) A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma in CARCINOGENESIS
By: Plantinga T.S., Costantini I., Heinhuis B., Huijbers A., Semango G., Kusters B., Netea M.G., Hermus A.R.M.M., Smit J.W.A., Dinarello C.A., Joosten L.A.B., Netea-Maier R.T. Year: 2013 (Cit.: 33 DOI: 10.1093/carcin/bgt092)