Imaging of human urothelial carcinoma samples using multimodal multiphoton microscopy
Autori: Baria E., Barone A., Nesi G., Pavone F.S., Cicchi R.
Affiliazione autori: European Laboratory for Non-Linear Spectroscopy, Via Nello Carrara 1, Sesto Fiorentino, 50019, Italy; Department of Surgery and Translational Medicine, University of Florence, Largo Brambilla 3, Florence, 50134, Italy; National Institute of Optics, National Research Council, Largo Enrico Fermi 6, Florence, 50125, Italy; Department of Physics, University of Florence, Via Sansone 1, Sesto Fiorentino, 50019, Italy
Abstract: We combined Second Harmonic Generation and Two-Photon Fluorescence for imaging ex vivo tissue sections of human bladder affected by urothelial carcinoma. We studied different grades of the tumor, and compared them to healthy bladder mucosa.
Parole chiavi: Nonlinear optics, Ex-vivo; Multi-modal; Multi-photon microscopy; Two photon fluorescence; Urothelial carcinoma, Microscopic examination