Titanate nanotube coatings on biodegradable photopolymer scaffolds

Year: 2013

Authors: Beke S., Korösi L., Scarpellini A., Anjum F., Brandi F.

Autors Affiliation: Department of Nanophysics, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy;
Department of Biotechnology, Nanophage Therapy Center, Enviroinvest Corporation, Kertváros u. 2, H-7632 Pécs, Hungary; Department of Nanochemistry, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy

Abstract: Rigid, biodegradable photopolymer scaffolds were coated with titanate nanotubes (TNTs) by using a spin-coating method. TNTs were synthesized by a hydrothermal process at 150 C under 4.7 bar ambient pressure. The biodegradable photopolymer scaffolds were produced by mask-assisted excimer laser photocuring at 308 nm. For scaffold coating, a stable ethanolic TNT sol was prepared by a simple colloid chemical route without the use of any binding compounds or additives. Scanning electron microscopy along with elemental analysis revealed that the scaffolds were homogenously coated by TNTs. The developed TNT coating can further improve the surface geometry of fabricated scaffolds, and therefore it can further increase the cell adhesion.


Volume: 33 (4)      Pages from: 2460  to: 2463

More Information: The authors thank Dr. Szilvia Papp (Department of Biotechnology, Nanophage Therapy Center, Enviroinvest Corporation, Pecs, Hungary) for the assistance on TEM measurements. Ilaria Romano (Department of Nanophysics, Istituto Italian di Tecnologia, Genova, Italy) is acknowledged for the help in the polymer synthesis. The financial supports from MFCDIAGN and FAGCNTER projects are also acknowledged.
KeyWords: Laser photocuring; Scaffolds; Titanate nanotubes; Tissue engineering; Poly(propylene fumarate)
DOI: 10.1016/j.msec.2013.01.066

Citations: 13
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