Area Prostriata in the Human Brain
Authors: Mikellidou K., Kurzawski J. W., Frijia F., Montanaro F., Greco V., Burr D. C. Morrone M. C.
Autors Affiliation: Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, via Savi 10, 56126 Pisa, Italy; Stella Maris Scientific Institute, Viale del Tirreno, 331, 56128 Calambrone, Italy; Department of Neuroscience, Psychology, Pharmacology and Child Health, University of Florence, Via di San Salvi 12, 50139 Florence, Italy; Unit of Neuroradiology, Fondazione CNR/Regione Toscana G. Monasterio, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy;
Istituto Nazionale di Ottica, CNR, Largo Enrico Fermi 6, 50125 Florence, Italy; Neuroscience Institute, CNR, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy
Abstract: Area prostriata is a cortical area at the fundus of the calcarine sulcus, described anatomically in humans [1-5] and other primates [6-9]. It is lightly myelinated and lacks the clearly defined six-layer structure evident throughout the cerebral cortex, with a thinner layer 4 and thicker layer 2 , characteristic of limbic cortex . In the marmoset and rhesus monkey, area prostriata has cortical connections with MT+ , the cingulate motor cortex , the auditory cortex , the orbitofrontal cortex, and the frontal polar cortices . Here we use functional magnetic resonance together with a wide-field projection system to study its functional properties in humans. With population receptive field mapping , we show that area prostriata has a complete representation of the visual field, clearly distinct from the adjacent area V1. As in the marmoset, the caudal-dorsal border of human prostriata-abutting V1-represents the far peripheral visual field, with eccentricities decreasing toward its rostral boundary. Area prostriata responds strongly to very fast motion, greater than 500 degrees/s. The functional properties of area prostriata suggest that it may serve to alert the brain quickly to fast visual events, particularly in the peripheral visual field.
Journal/Review: CURRENT BIOLOGY
Volume: 27 (19) Pages from: 3056-1 to: 3056-8
More Information: This research was supported by the European Research Council under the European UnionDOI: 10.1016/j.cub.2017.08.065Citations: 24data from “WEB OF SCIENCE” (of Thomson Reuters) are update at: 2022-05-22References taken from IsiWeb of Knowledge: (subscribers only)Connecting to view paper tab on IsiWeb: Click hereConnecting to view citations from IsiWeb: Click here